As manager of VARI’s Genomics Core and interim manager of VARI’s Bioinformatics and Biostatistics Core, Marie Adams is an expert in the latest next-generation sequencing techniques. After earning an M.S. in genetics from Iowa State University, she served as a research assistant in the Division of Hematology/Oncology at Cincinnati Children’s Hospital where she evaluated novel small-molecular inhibitors as potential cancer therapies. She then moved to University of Wisconsin Biotechnology Center as the research lead and next-generation sequencing core manager for the DNA Sequencing Facility. Marie joined VARI in September 2016.
Dr. Tim Triche, Jr., earned his A.B. in chemistry from Cornell University, followed by an M.S. in biostatistics and a Ph.D. in statistical genetics from University of Southern California. Prior to joining Van Andel Research Institute’s Center for Epigenetics in 2017, he served as a postdoctoral fellow in the Jane Anne Nohl Division of Hematology at USC’s Norris Comprehensive Cancer Center, where he studied the roles of cellular and immune senescence in benign and malignant blood disorders, including acute myeloid leukemia and pediatric leukemia. He has been a key member of The Cancer Genome Atlas Research Network since 2011, and has contributed to more than a dozen of the consortium’s publications in journals such as Nature and Cell. As a statistician with interests in both basic and translational research, Dr. Triche’s work focuses on improving patient outcomes and quality of life through the design of randomized clinical trials, which are critical components of moving promising therapies from the lab to the doctor’s office.
Dr. Ian Beddows joined Van Andel Research Institute’s Bioinformatics and Biostatistics Core in February 2018. He received his Bachelor’s in biology from Northern Michigan University followed by a M.S. and Ph.D. from the University of Düsseldorf in Germany. His graduate research in population genetics focused on understanding genomic variation in wild populations using high-throughput sequence data.
As a bioinformatics scientist, Dr. Ben Johnson focuses on the analysis of various high-throughput sequencing approaches and their applications to the biomedical sciences, as well as teaching, mentoring and outreach. He earned a B.S. in biology and biochemistry from Calvin College and his Ph.D. in microbiology and molecular genetics from Michigan State University. As part of his graduate work, he developed computational tools (HAARP and SPARTA) to identify novel inhibitors of pH-dependent adaptation in Mycobacterium tuberculosis (TB) in order make treatment more effective and, as a result, shorter. He joined VARI’s Bioinformatics and Biostatistics Core in May 2016.
Zach Madaj joined the Bioinformatics and Biostatistics Core as a biostatistician in 2015. A graduate of the University of Michigan (M.S., biostatistics) and Grand Valley State University (B.S., mathematics), he brings statistical analysis, consulting, and teaching experience to the core. His focus is on study design, statistical analysis, and the development of educational resources.
Emily Wolfrum joined the Bioinformatics and Biostatistics Core as a biostatistician in 2017. After earning her B.S. in biology from Aquinas College, she completed her Master’s of Public Health at University of Michigan with a focus on hospital and molecular epidemiology. She brings both lab experience and knowledge of epidemiological theory and application to the Core.